Metastatic adult-type non-rhabdomyosarcoma soft tissue sarcomas in children and adolescents: A cohort study from the European paediatric Soft tissue sarcoma Study Group.
Ferrari A, Orbach D, Casanova D, van Noesel MM, Berlanga P, Brennan B, Corradini N, Schoot RA, Ramirez-Villar GA, Hjalgrim LL, Alaggio R, Guillen Burrieza G, Safwat A, Cameron A, van Rijn RR, Minard-Colin V, Zanetti I, Bisogno G, Chisholm J, Merks JHM. Cancer 2023 Apr 21. doi: 10.1002/cncr.34814. Online ahead of print
Pediatric non-rhabdomyosarcoma soft tissue sarcomas form a heterogeneous group of rare tumors. While…
The significance of margins in pediatric Non-Rhabdomyosarcoma soft tissue sarcomas: Consensus on surgical margin definition harmonization from the INternational Soft Tissue SaRcoma ConsorTium (INSTRuCT)
Sparber-Sauer M, Ferrari A, Spunt SL, Vokuhl C, Casey D, Lautz TB, Meyer WH, Walterhouse DO, Pajtler KW, Alaggio R, Schmidt A, Safwat A, Timmermann B, Dall'Igna P, Chen S, Weiss AR, Orbach D.
Pediatr Blood Cancer 2023 Feb;70(2):e30116. doi: 10.1002/pbc.30116. Epub 2022 Nov 28, 2023 Feb 6. doi: 10.1002/cam4.5671. Online ahead of print.
Margin status following surgery in children, adolescents and young adults with soft tissue sarcomas…
Malignant ectomesenchymoma in children: The European pediatric Soft tissue sarcoma Study Group experience
Milano GM, Orbach D, Casanova M, Berlanga P, Schoot R, Corradini N, Brennan B, Ramirez-Villar G, Lyngsie Hjalgrim L, van Noesel M, Alaggio R, Ferrari A
Pediatr Blood Cancer 2023 Feb;70(2):e30116. doi: 10.1002/pbc.30116. Epub 2022 Nov 28
This is a short report on 10 cases of malignant ectomesenchymoma (MEM) enrolled in the EpSSG NRSTS…
Metastatic rhabdomyosarcoma with exclusive distant lymph node involvement: A European Pediatric Soft tissue sarcoma Study Group (EpSSG) report
Mercolini F, Merks JHM, Minard-Colin V, Cameron A, Terwisscha van Scheltinga S, Sher O, Fichera G, Orbach D, Glosli H, Coppadoro B, Gallego S, Chisholm J, Bisogno G. Pediatr Blood Cancer
. 2023 Mar;70(3):e30143. doi: 10.1002/pbc.30143.
Prognosis of patients with metastatic rhabdomyosarcoma is still poor. However, efforts must be made…
Rhabdomyosarcoma with unknown primary tumor site: A report from European pediatric Sift tissue sarcoma Study Group (EpSSG)
Affinita MC, Merks JHM, Chisholm JC, Haouy S, Rome A, Rabusin M, Brennan B, Bisogno G. Pediatr Blood Cancer. 2022 Sep 12:e29967. doi: 10.1002/pbc.29967. Online ahead of print.
Abstract Background: Rhabdomyosarcoma (RMS) is an aggressive malignancy, and 20% of children present…
Epithelioid hemangioendothelioma in Children: the European pediatric soft tissue sarcoma study group (EpSSG) Experience
Orbach D, van Noesel MM, Brennan B, Corradini N, Alaggio R, Ben Arush M, Schoot RA, Berlanga P, Zanetti I, Lyngsie Hjalgrim L, De Corti F, Ramirez G, Casanova M, Ferrari A. Pediatr Blood Cancer 2022 Jul 16;e29882. doi: 10.1002/pbc.29882. Online ahead of print.
Abstract The European pediatric Soft tissue sarcoma Study Group analyzed all children with…
Therapy and Prognostic Significance of Regional Lymph node involvement in Embryonal Rhabdomyosarcoma: a Report from the European paediatric Soft tissue Sarcoma Study Group
Ben Arush M, Minard-Colin V, Scarzello G, Davila Fajardo, R, Terwisscha Van Scheltinga S, Bernier-Chastagner V, Jenney M, Gallego S, Zanetti I, Česen M, Merks JHM, G. Bisogno European Journal of Cancer Eur J Cancer 2022 Jun 25;172:119-129. doi: 10.1016/j.ejca.2022.05.033. Online ahead of print
Abstract Purpose: Regional lymph node disease (N1) is a component of the risk-based treatment…
Congenital spindle cell rhabdomyosarcoma: An international cooperative analysis.
Whittle S, Venkatramani R, Schönstein A, D Pack S, Alaggio R, Vokuhl C, Rudzinski ER, Wulf AL, Zin A, Gruver JR, Arnold MA, Merks JHM, Hettmer S, Koscielniak E, Barr FG, Hawkins DS, Bisogno G, Sparber-Sauer M. Eur J Cancer 2022 Jun;168:56-64. doi: 10.1016/j.ejca.2022.03.022. Epub 2022 Apr 19.
Abstract Background: Spindle cell rhabdomyosarcoma (RMS) is a rare variant of RMS accounting for up…
Metastatic Rhabdomyosarcoma: Results of the European Paediatric Soft Tissue Sarcoma Study Group MTS 2008 Study and Pooled Analysis With the Concurrent BERNIE Study.
Schoot RA, Chisholm JC, Casanova M, Minard-Colin V, Geoerger B, Cameron AL, Coppadoro B, Zanetti I, Orbach D, Kelsey A, Rogers T, Guizani C, Elze M, Ben-Arush M, McHugh K, van Rijn RR, Ferman S, Gallego S, Ferrari A, Jenney M, Bisogno G, Merks JHM J Clin Oncol. 2022 Jun 16:JCO2102981. doi: 10.1200/JCO.21.02981. Online ahead of print.PMID: 35709412
Abstract Purpose: Outcome for patients with metastatic rhabdomyosarcoma (RMS) is poor. This study…
Adolescents and young adults with rhabdomyosarcoma treated in the European paediatric Soft tissue sarcoma Study Group (EpSSG) protocols: a cohort study.
Ferrari A, Chisholm J, Jenney M, Minard-Colin V, Orbach D, Casanova M, Guillen G, Glosli H, van Rijn RR, Schoot RA, Cameron AL, Rogers T, Alaggio R, Ben-Arush M, Mandeville HC, Devalck C, Defachelles AS, Coppadoro B, Bisogno G, Merks JHM. Lancet Child Adolesc Health. 2022 Jun 8;S2352-4642(22)00121-3. doi: 10.1016/S2352-4642(22)00121-3. Online ahead of print.
Abstract Background: Adolescent and young adult patients with rhabdomyosarcoma often have poorer…
In transit metastases in children, adolescents and young adults with localized rhabdomyosarcoma of the distal extremities: Analysis of the EpSSG RMS 2005 study.
Terwisscha van Scheltinga CEJ, Wijnen MHWA, Martelli H, Guerin F, Rogers T, Craigie RJ, Guillén Burrieza G, Dall'Igna P, De Corti F, Smeulders N, van Rijn RR, Dávila Fajardo R, Mandeville HC, Zanetti I, Coppadoro B, Minard-Colin V, Jenney M, Bisogno G, van Noesel MM, van der Steeg AFW, Merks JHM. European journal of surgical oncology: the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology Follow journal, doi: 10.1016/j.ejso.2022.03.001
Abstract In-transit metastases (ITM) are defined as metastatic lymph nodes or deposits occurring…
Perianal/perineal rhabdomyosarcoma: results of the SIOP MMT-95, ITALIAN RMS-96, and EpSSG RMS-2005 studies
Rogers T, Zanetti I, Coppadoro B, Martelli H, Jenney M, Minard-Colin V, Terwisscha van Scheltinga SEJ, Skerritt C, Dávila Fajardo R, Guérin F, Kelsey A, Merks JHM, Mandeville H, Guillén G, Glosli H, Bisogno G. Pediatr Blood Cancer 2022 Apr 23;e29739. doi: 10.1002/pbc.29739. Online ahead of print.
Abstract Background/objectives: Rhabdomyosarcoma of the perianal/perineal region (PRMS) is rare,…
Localised rhabdomyosarcoma in infants (< 12 months) and young children (12-36 months of age) treated on the EpSSG RMS 2005 study
Slater O, Gains J, Kelsey A, De Corti F, Zanetti I, Coppadoro B, Jorgensen M, Gallego S, Orbach D, Glosli H, Cesen M, Gaze MN, Smeulders N, Ferrari A, Jenney M, Minard-Colin V, Bisogno G, .Merks JHM for the European paediatric Soft tissue sarcoma Study Group Eur J Cancer. 2022 Jan;160:206-214. doi: 10.1016/j.ejca.2021.10.031. Epub 2021 Dec 2.
Abstract Background: Infants (<12 months) with rhabdomyosarcoma have historically had poorer outcome…
Congenital rhabdomyosarcoma: A report from the European paediatric Soft tissue sarcoma Study Group
Bisogno G, Minard-Colin V, Arush MB, Daragjati J, Coppadoro B, Gallego S, Alaggio R, Smeulders N, Mudry P, Zin A, Merks JHM, Slater O. Pediatr Blood Cancer. 2021 Sep 28:e29376. doi: 10.1002/pbc.29376.
Abstract Procedure Congenital rhabdomyosarcoma (RMS) represents a challenging disease due to its…
Role of 18F-FDG-PET/CT in the staging of metastatic rhabdomyosarcoma: a report from the European paediatric Soft tissue sarcoma Study Group.
Mercolini F, Zucchetta P, Jehanno N, Corradini N, Van Rijn RR, Rogers T, Cameron A, Scarzello G, Coppadoro B, Minard-Colin V, Gallego S, Chisholm J, Merks JH, Bisogno G Eur J Cancer. 2021 Aug 9;155:155-162. doi: 10.1016/j.ejca.2021.07.006. Online ahead of print.
Abstract Background: Initial staging of rhabdomyosarcoma is crucial for prognosis and to tailor the…
Randomized Phase II Trial of Vincristine-Irinotecan With or Without Temozolomide, in Children and Adults With Relapsed or Refractory Rhabdomyosarcoma: A European Paediatric Soft tissue Sarcoma Study Group and Innovative Therapies for Children With Cancer Trial.
Defachelles AS, Bogart E, Casanova M, Merks JHM, Bisogno G, Calareso G, Gallego Melcon S, Gatz SA, Le Deley MC, McHugh K, Probst A, Rocourt N, van Rijn RR, Wheatley K, Minard-Colin V, Chisholm JC. J Clin Oncol. 2021 Aug 3:JCO2100124. doi: 10.1200/JCO.21.00124. Online ahead of print.PMID: 34343032
Abstract Purpose: The VIT-0910 trial was conducted to evaluate efficacy and safety of the…
The Impact of Radiation Therapy in Children and Adolescents With Metastatic Rhabdomyosarcoma.
Cameron AL, Elze MC, Casanova M, Geoerger B, Gaze MN, Minard-Colin V, McHugh K, van Rijn RR, Kelsey A, Martelli H, Mandeville H, Bisogno G, Lowis S, Ronghe M, Orbach D, Guizani C, Fürst-Recktenwald S, Chisholm JC, Merks JHM,European Paediatric Soft Tissue Sarcoma Study Group (EpSSG) and the European Innovative Therapies for Children with Cancer (ITCC) Consortium. Int J Radiat Oncol Biol Phys. 2021 Jul 1:S0360-3016(21)00823-3. doi: 10.1016/j.ijrobp.2021.06.031. Online ahead of print.
Abstract Purpose: There is limited evidence to define the role of radiation therapy in children with…
Paediatric non-rhabdomyosarcoma soft tissue sarcomas: the prospective NRSTS 2005 study by the European Pediatric Soft Tissue Sarcoma Study Group (EpSSG)
Ferrari A, van Noesel M, Brennan B, Zanetti I, Casanova M, Berlanga P, Merks JHM, Alaggio R, Schifflers S, Ramirez Vilar G, Giraudo C, Guillén Burrieza G, Safwat A, Bisogno G, De Salvo
GL, Orbach D The Lancet Child & Adolescent Health June 2021, doi: 10.1016/S2352-4642(21)00159-0
Summary Background A standardised approach to treatment of paediatric non-rhabdomyosarcoma soft…
Non-parameningeal head and neck rhabdomyosarcoma in children, adolescents, and young adults: Experience of the European paediatric Soft tissue sarcoma Study Group (EpSSG) - RMS2005 study
Glosli H, Bisogno G, Kelsey A, Chisholm J, Gaze M, Kolb F, McHugh K, Shipley J, Gallego S, Merks JHM, Smeele LE, Mandeville H, Ferrari A, Minard-Colin V, Corradini N, Jenney M, Zanetti I, De Salvo GL, Orbach D, EpSSG members Eur J Cancer 2021 Jul;151:84-93. doi: 10.1016/j.ejca.2021.04.007. Epub 2021 May 7.
Background/objectives: The primary aim of this study was to analyse and evaluate the impact of…
Pathology of childhood rhabdomyosarcoma: A consensus opinion document from the Children's Oncology Group, European Paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.
Rudzinski ER, Kelsey A, Vokuhl C, Linardic CM, Shipley J, Hettmer S, Koscielniak E, Hawkins DS, Bisogno G. Pediatr Blood Cancer. 2021 Mar;68(3):e28798. doi: 10.1002/pbc.28798.
Abstract The diagnosis and classification of rhabdomyosarcoma (RMS) has undergone several shifts…
