Publications

Genomic complexity in pediatric synovial sarcomas (SYNOBIO study): the European Pediatric Soft tissue Sarcoma Group (EpSSG) experience

Orbach D, Mosseri V, Pissaloux D, Pierron G, Brennan B, Ferrari A, Chibon F, Bisogno G, De Salvo GL, Chakiba C, MD, Corradini N, Minard-Colin V, Kelsey A,Ranchère-Vince D. Genomic complexity in pediatric synovial sarcomas (SYNOBIO study): the European Pediatric Soft tissue Sarcoma Group (EpSSG) experience. Cancer Medicine. 2017. DOI: 10.1002/cam4.1415

Abstract A genomic index (GI) tool using array comparative genomic hybridization (aCGH) on tumor…

Alveolar Soft Part Sarcoma in children and adolescents: the European Paediatric Soft Tissue Sarcoma Study Group prospective trial (EpSSG NRSTS 2005)

Brennan B, Zanetti I, Orbach D, Gallego S, Francotte N, Van Noesel M, Kelsey A, Casanova M, De Salvo GL, Bisogno G, Ferrari A. Alveolar Soft Part Sarcoma in children and adolescents: the European Paediatric Soft Tissue Sarcoma Study Group prospective trial (EpSSG NRSTS 2005). Pediatr Blood Cancer. 2017 e26942. DOI:101002/pbc.26942

Abstract Background As alveolar soft part sarcomas (ASPS) are rare with no prospective series within…

Paratesticular rhabdomyosarcoma in children and adolescents-Outcome and patterns of relapse when utilizing a nonsurgical strategy for lymph node staging: Report from the International Society of Paediatric Oncology (SIOP) Malignant Mesenchymal Tumour 89 and 95 studies.

Rogers T, Minard-Colin V, Cozic N, Jenney M, Merks JHM, Gallego S, Devalck C, Gaze MN, Kelsey A, Oberlin O, Stevens M, Spicer RD, Bergeron C, Martelli H.
Pediatr Blood Cancer. 2017 Sep;64(9). doi: 10.1002/pbc.26486. Epub 2017 Feb 16.

Abstract Purpose: To report the results from International Society of Pediatric Oncology (SIOP)…

Open-label, multicentre, randomised, phase II study of the EpSSG and the ITCC evaluating the addition of bevacizumab to chemotherapy in childhood and adolescent patients with metastatic soft tissue sarcoma (the BERNIE study)

Chisholm J, Merks JHM, Casanova M, Bisogno G, Orbach D, Gentet JC, Thomassin-Defachelles A, Chastagner P, Lowis S, Ronghe M, McHugh K, van Rijn RR, Hilton M, Bachir J, Furst-Recktenwald S, Geoerger B, Oberlin O. Open-label, multicentre, randomised, phase II study of the EpSSG and the ITCC evaluating the addition of bevacizumab to chemotherapy in childhood and adolescent patients with metastatic soft tissue sarcoma (the BERNIE study). Eur J of Cancer. 2017 Sept 83:177-184. DOI: 10.1016/j.ejca.2017.06.015

Abstract Purpose: We evaluated the role of bevacizumab as part of the multi-modality treatment of…

The EpSSG NRSTS 2005 treatment protocol for desmoid-type fibromatosis in children: an international prospective case series

Orbach D, Brennan B, Bisogno G, Van Noesel M, Minard-Colin V, Daragjati J, Casanova M, Corradini N, Zanetti I, De Salvo GL, Defachelles AS, Kelsey A, Ben Arush M, Francotte N, Ferrari A. The EpSSG NRSTS 2005 treatment protocol for desmoid-type fibromatosis in children: an international prospective case series. The Lancet child-adol. 2017 Sept DOI:org/10.1016/S2352-4642(17)30045-7

Background In 2005, the European Pediatric Soft Tissue Sarcoma Study Group (EpSSG) proposed a…

Surgery alone is sufficient therapy for children and adolescents with low-risk synovial sarcoma: A joint analysis from the European paediatric soft tissue sarcoma Study Group and the Children's Oncology Group

Ferrari A, Chi YY, De Salvo GL, Orbach D, Brennan B, Randall RL, McCarville MB, Black JO, Alaggio R, Hawkins DS, Bisogno G, Spunt SL. Surgery alone is sufficient therapy for children and adolescents with low-risk synovial sarcoma: A joint analysis from the European paediatric soft tissue sarcoma Study Group and the Children's Oncology Group. Eur J Cancer. 2017 Apr 6;78:1-6. DOI: 10.1016/j.ejca.2017.03.003

Abstract Background: Multimodal risk-adapted treatment is used in paediatric protocols for synovial…

Access to clinical trials for adolescents with Soft tissue sarcomas: enrollment in European pediatric Soft tissue sarcoma Study Group (EpSSG) protocols

Ferrari A, Trama, De Paoli, Bergeron, Merks, Jenney, Orbach, Chisholm, Gallego, Glosli, De Salvo, Botta, Gatta, Bisogno. Access to clinical trials for adolescents with Soft tissue sarcomas: enrollment in European pediatric Soft tissue sarcoma Study Group (EpSSG) protocols. Pediatr Blood Cancer. 2017 Jun;64(6). DOI: 10.1002/pbc.26348

Abstract Background Adolescents with cancer are enrolled in clinical trials at far lower rates than…

Outcome of extracranial malignant rhabdoid tumours in children registered in the European Paediatric Soft Tissue Sarcoma Study Group Non-Rhabdomyosarcoma Soft Tissue Sarcoma 2005 Study-EpSSG NRSTS 2005

Brennan B, De Salvo GL, Orbach D, De Paoli A, Kelsey A, Mudry P, Francotte N, Van Noesel M, Bisogno G, Casanova M, Ferrari A. Outcome of extracranial malignant rhabdoid tumours in children registered in the European Paediatric Soft Tissue Sarcoma Study Group Non-Rhabdomyosarcoma Soft Tissue Sarcoma 2005 Study-EpSSG NRSTS 2005. Eur J Cancer. 2016 Jun;60:69-82. DOI: 10.1016/j.ejca.2016.02.027

Abstract Background: Extracranial malignant rhabdoid tumours (MRT) are rare lethal childhood cancers…

Conservative strategy in infantile fibrosarcoma is possible: The European paediatric Soft tissue sarcoma Study Group experience

Orbach D, Brennan B, De Paoli A, Gallego S, Mudry P, Francotte N, van Noesel M, Kelsey A, Alaggio R, Ranchère D, De Salvo GL, Casanova M, Bergeron C, Merks, JH, Jenney M, Stevens MC, Bisogno G, Ferrari A. Conservative strategy in infantile fibrosarcoma is possible: The European paediatric Soft tissue sarcoma Study Group experience. Eur J Cancer. 2016 Apr;57:1-9. DOI: 10.1016/j.ejca.2015.12.028

Abstract Background Infantile fibrosarcoma (IFS) is a very rare disease occurring in young infants…

Synovial sarcoma in children and adolescents: the European Pediatric Soft Tissue Sarcoma Study Group prospective trial (EpSSG NRSTS 2005)

Ferrari A, De Salvo GL, Brennan B, van Noesel MM, De Paoli A, Casanova M, Francotte N, Kelsey A, Alaggio R, Oberlin O, Carli M, Ben-Arush M, Bergeron C, Merks JH, Jenney M, Stevens MC, Bisogno G, Orbach D. Synovial sarcoma in children and adolescents: the European Pediatric Soft Tissue Sarcoma Study Group prospective trial (EpSSG NRSTS 2005). Ann Oncol. 2015 Mar;26(3):567-72. DOI: 10.1093/annonc/mdu562

Abstract Background: To report the results of the first European prospective nonrandomized trial…

Surgical compliance with guidelines for paratesticular rhabdomyosarcoma (RMS). Data from the European Study on non-metastatic RMS

Cecchetto G, De Corti F, Rogers T, Martelli H. Surgical compliance with guidelines for paratesticular rhabdomyosarcoma (RMS). Data from the European Study on non-metastatic RMS. J Pediatr Surg. 2012 Nov;47(11):2161-2. DOI: 10.1016/j.jpedsurg.2012.08.004