Parameningeal Rhabdomyosarcoma: Results of the European Pediatric Soft Tissue Sarcoma Study Group RMS 2005 Study.
Schoot RA, Taselaar P, Scarzello G, Kolb F, Coppadoro B, Horst ST, Mandeville H, Ferrari A, Hladun R, Helfre S, Ferman S, Kelsey A, Hol MLF, Devalck C, Ben-Arush M, Orbach D, Chisholm J, Jenney M, Minard-Colin V, Bisogno G, Merks JHM.
Head Neck. 2024 Nov 15. doi: 10.1002/hed.27994. Online ahead of print.
PMID: 39545397
Localized incompletely resected standard risk rhabdomyosarcoma in children and adolescents: Results from the European Paediatric Soft Tissue Sarcoma Study Group RMS 2005 trial.
Mandeville HC, Bisogno G, Minard-Colin V, Alaggio R, Ben-Arush M, Chargari C, Coppadoro B, Craigie R, Devalck C, Ferman S, Ferrari A, Glosli H, Alvaro RH, Hol M, Mudry P, Orbach D, Albiac MR, Merks JHM, Jenney MEM.Cancer. 2024 Jul 26. doi: 10.1002/cncr.35497. Online ahead of print.PMID: 39058728
Reappraisal of prognostic factors used in the European Pediatric Soft Tissue Sarcoma Study Group RMS 2005 study for localized rhabdomyosarcoma to optimize risk stratification and generate a prognostic nomogram.
De Salvo GL, Del Bianco P, Minard-Colin V, Chisholm J, Jenney M, Guillen G, Devalck C, Van Rijn R, Shipley J, Orbach D, Kelsey A, Rogers T, Guerin F, Scarzello G, Ferrari A, Cesen Mazic M, Merks JHM, Bisogno G; European Pediatric Soft Tissue Sarcoma Study Group.Cancer. 2024 Jul 1;130(13):2351-2360. doi: 10.1002/cncr.35258. Epub 2024 Feb 24.PMID: 38400828
This study used data from patients enrolled in the EpSSG RMS 2005 study to investigate the role of…
Treatment at relapse for synovial sarcoma of children and adolescents: A multi-institutional European retrospective analysis.
Ferrari A, Orbach D, Bergamaschi L, Schoot RA, van Noesel MM, Di Carlo D, Bisogno G, Alaggio R, Milano GM, Chiaravalli S, Fuccillo F, Laurence V, Corradini N, Gasparini P, Vennarini S, Pasquali S, Casanova M.Pediatr Blood Cancer. 2024 Jul;71(7):e31038. doi: 10.1002/pbc.31038. Epub 2024 Apr 28.PMID: 38679840
Indeterminate pulmonary nodules in non‐rhabdomyosarcoma soft tissue sarcoma: A study of the European paediatric Soft Tissue Sarcoma Study Group.
Giraudo C, Schoot R, Cardoen L, Stramare R, Coppadoro B, Bisogno G, Bouhamama A, Brennan B, Brisse HJ, Orbach D, Coma A, Di Paolo PL, Fayard C, McDonald L, Moalla S, Morosi C, Pace E, Tang V, van Noesel M, Ferrari A, van Rijn R. Cancer 2023 Oct 17. doi: 10.1002/cncr.35061. Online ahead of print.
Radiologists should be aware of the classification of indeterminate pulmonary nodules in…
Frontline and Relapsed Rhabdomyosarcoma (FAR-RMS) Clinical Trial: A Report from the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG).
Chisholm J, Mandeville H, Adams M, Minard-Collin V, Rogers T, Kelsey A, Shipley J, van Rijn RR, de Vries I, van Ewijk R, de Keizer B, Gatz SA, Casanova M, Hjalgrim LL, Firth C, Wheatley K, Kearns P, Liu W, Kirkham A, Rees H, Bisogno G, Wasti A, Wakeling S, Heenen D, Tweddle DA, Merks JHM, Jenney M.Cancers (Basel). 2024 Feb 29;16(5):998. doi: 10.3390/cancers16050998.PMID: 38473359
This review article describes the rationale, design and study questions of the international EpSSG…
Quantitative diffusion-weighted MRI response assessment in rhabdomyosarcoma: an international retrospective study on behalf of the European paediatric Soft tissue sarcoma Study Group Imaging Committee.
van Ewijk R, Chatziantoniou C, Adams M, Bertolini P, Bisogno G, Bouhamama A, Caro-Dominguez P, Charon V, Coma A, Dandis R, Devalck C, De Donno G, Ferrari A, Fiocco M, Gallego S, Giraudo C, Glosli H, Ter Horst SAJ, Jenney M, Klein WM, Leemans A, Leseur J, Mandeville HC, McHugh K, Merks JHM, Minard-Colin V, Moalla S, Morosi C, Orbach D, Ording Muller LS, Pace E, Di Paolo PL, Perruccio K, Quaglietta L, Renard M, van Rijn RR, Ruggiero A, Sirvent SI, De Luca A, Schoot RA. Pediatr Radiol. 2023 Nov;53(12):2539-2551. doi: 10.1007/s00247-023-05745-z. Epub 2023 Sep 8.PMID: 37682330
Biological Role and Clinical Implications of MYOD1L122R Mutation in Rhabdomyosarcoma.
Di Carlo D, Chisholm J, Kelsey A, Alaggio R, Bisogno G, Minard-Colin V, Jenney M, Dávila Fajardo R, Merks JHM, Shipley JM, Selfe JL
Recent advances have greatly improved our understanding of rhabdomyosarcoma (RMS), a type of cancer,…
Maintenance Chemotherapy for Patients with Rhabdomyosarcoma
Bisogno G, Minard-Colin V, Jenney M, Ferrari A, Chisholm J, Di Carlo D, Hjalgrim LL, Orbach D, Merks JHM, Casanova M. Cancers (Basel). 2023 Aug 7;15(15):4012. doi: 10.3390/cancers15154012.
The updated results of the RMS2005 randomized study confirm that patients with non-metastatic high…
Outcomes in lung-only metastatic rhabdomyosarcoma: An analysis of data from the European paediatric Soft tissue sarcoma Study Group MTS 2008 study
Chisholm JC, Schoot RA, Cameron AL, Casanova M, Minard-Colin V, Coppadoro B, Garrido B, Rogers B, Orbach D, Glosli H, Ben-Arush M, Ferman S, Scarzello G, van Rijn RR, Hladun R, Corradini N, Ferrari A, Jenney M, Bisogno G, Merks JHM. EJC 2023. https://doi.org/10.1016/j.ejcped.2023.100018
Among patients with metastatic rhabdomyosarcoma, outcomes are better in patients for whom lung is…
Time to broaden the eligibility criteria in paediatric oncology trials? An analysis of patients with rhabdomyosarcoma non-eligible to the EpSSG RMS2005 trial
Bisogno G, De Salvo GL, Minard-Colin V, Davila Fajardo R, Coppadoro B, Jenney M, Ferrari A, Hladun Alvaro R, Dall’Igna P, Glosli H, Merks JHM. EJC. 2023 May doi: https://doi.org/10.1016/j.ejcped.2023.100014
Clinical trials for pediatric rhabdomyosarcoma (RMS) include specific rules to ensure patient safety…
Outcome of patients with undifferentiated embryonal sarcoma of the liver treated according to European soft tissue sarcoma protocols
Guérin F, Martelli H, Rogers T, Zanetti I, Terwisscha van Scheltinga S, De Corti F, Guillen Burrieza G, Minard-Colin V, Orbach D, van Noesel MM, Karanian M, Dávila Fajardo R, Merks JHM, Ferrari A, Bisogno G, Pediatr Blood Cancer. 2023 Jul;70(7):e30374. doi: 10.1002/pbc.30374. Epub 2023 Apr 21.
Highlights of the paper: Neoadjuvant chemotherapy for pediatric patients with UESL increases the…
Nonmetastatic Rhabdomyosarcoma in Children and Adolescents: Overall Results of the European Pediatric Soft Tissue Sarcoma Study Group RMS2005 Study
Bisogno G, Minard-Colin V, Zanetti I, Ferrari A, Gallego S, Davila Fajardo R, Mandeville H, Kelsey A, Alaggio R, Orbach D, Terwisscha van Scheltinga S, Guillen Burrieza G, Ben-Arush M, Glosli H, Mudry P, Ferman S, Devalck C, Defachelles AS, Merks JHM, Jenney M.
J Clin Oncol 2023 May 1;41(13):2342-2349.doi: 10.1200/JCO.22.02093. Epub 2023 Feb 27.
The study was open from October 1st, 2005, to December 31st, 2016 and 1,733 patients were enrolled…
Intra-abdominal desmoplastic small round cell tumor: The European pediatric Soft tissue sarcoma Study Group (EpSSG) experience.
Berlanga P, Orbach D, Schoot RA, Casanova M, Alaggio R, Corradini N, Brennan B, Ramirez-Villar GL, Hjalgrim L, Chisholm J, Bisogno G, Coppadoro B, Safwat A, Merks JHM, Guillen Burrieza G, van Noesel MM, Ferrari A.Pediatr Blood Cancer 2023 May 26;e30447. doi: 10.1002/pbc.30447.
Desmoplastic small round cell tumor (DSRCT) is an ultra-rare and aggressive mesenchymal tumor…
Metastatic adult-type non-rhabdomyosarcoma soft tissue sarcomas in children and adolescents: A cohort study from the European paediatric Soft tissue sarcoma Study Group.
Ferrari A, Orbach D, Casanova D, van Noesel MM, Berlanga P, Brennan B, Corradini N, Schoot RA, Ramirez-Villar GA, Hjalgrim LL, Alaggio R, Guillen Burrieza G, Safwat A, Cameron A, van Rijn RR, Minard-Colin V, Zanetti I, Bisogno G, Chisholm J, Merks JHM. Cancer 2023 Apr 21. doi: 10.1002/cncr.34814. Online ahead of print
Pediatric non-rhabdomyosarcoma soft tissue sarcomas form a heterogeneous group of rare tumors. While…
The significance of margins in pediatric Non-Rhabdomyosarcoma soft tissue sarcomas: Consensus on surgical margin definition harmonization from the INternational Soft Tissue SaRcoma ConsorTium (INSTRuCT)
Sparber-Sauer M, Ferrari A, Spunt SL, Vokuhl C, Casey D, Lautz TB, Meyer WH, Walterhouse DO, Pajtler KW, Alaggio R, Schmidt A, Safwat A, Timmermann B, Dall'Igna P, Chen S, Weiss AR, Orbach D.
Pediatr Blood Cancer 2023 Feb;70(2):e30116. doi: 10.1002/pbc.30116. Epub 2022 Nov 28, 2023 Feb 6. doi: 10.1002/cam4.5671. Online ahead of print.
Margin status following surgery in children, adolescents and young adults with soft tissue sarcomas…
Malignant ectomesenchymoma in children: The European pediatric Soft tissue sarcoma Study Group experience
Milano GM, Orbach D, Casanova M, Berlanga P, Schoot R, Corradini N, Brennan B, Ramirez-Villar G, Lyngsie Hjalgrim L, van Noesel M, Alaggio R, Ferrari A
Pediatr Blood Cancer 2023 Feb;70(2):e30116. doi: 10.1002/pbc.30116. Epub 2022 Nov 28
This is a short report on 10 cases of malignant ectomesenchymoma (MEM) enrolled in the EpSSG NRSTS…
Metastatic rhabdomyosarcoma with exclusive distant lymph node involvement: A European Pediatric Soft tissue sarcoma Study Group (EpSSG) report
Mercolini F, Merks JHM, Minard-Colin V, Cameron A, Terwisscha van Scheltinga S, Sher O, Fichera G, Orbach D, Glosli H, Coppadoro B, Gallego S, Chisholm J, Bisogno G. Pediatr Blood Cancer
. 2023 Mar;70(3):e30143. doi: 10.1002/pbc.30143.
Prognosis of patients with metastatic rhabdomyosarcoma is still poor. However, efforts must be made…
Rhabdomyosarcoma with unknown primary tumor site: A report from European pediatric Sift tissue sarcoma Study Group (EpSSG)
Affinita MC, Merks JHM, Chisholm JC, Haouy S, Rome A, Rabusin M, Brennan B, Bisogno G. Pediatr Blood Cancer. 2022 Sep 12:e29967. doi: 10.1002/pbc.29967. Online ahead of print.
Abstract Background: Rhabdomyosarcoma (RMS) is an aggressive malignancy, and 20% of children present…
Epithelioid hemangioendothelioma in Children: the European pediatric soft tissue sarcoma study group (EpSSG) Experience
Orbach D, van Noesel MM, Brennan B, Corradini N, Alaggio R, Ben Arush M, Schoot RA, Berlanga P, Zanetti I, Lyngsie Hjalgrim L, De Corti F, Ramirez G, Casanova M, Ferrari A. Pediatr Blood Cancer 2022 Jul 16;e29882. doi: 10.1002/pbc.29882. Online ahead of print.
Abstract The European pediatric Soft tissue sarcoma Study Group analyzed all children with…
